基于铜催化的亚砜亚胺与芳肼的N-芳基化反应研究

In this paper, the method of denitrifying Nitrogen to realize N-arylation of sulfoximine is studied, and a series of N-arylation products of sulfoximine compounds are prepared. The authors used phenyl sulfoximine and phenylhydrazine hydrochloride as reaction substrates, and screened the factors involved in the reaction, such as catalyst, oxidant, solvent. The optimal reaction conditions for the aryl sulfoxide as the aryl source and the sulfoxide imine N-arylation reaction were successfully prepared. Under the optimal conditions, 21 sulfoximine imine N-arylation products were successfully prepared..