LTP的分子机制研究进展
Research progress of LTP molecular mechanism
突触可塑性的改变与阿尔茨海默病、癫痫、慢性痛、药物成瘾性和精神分裂症等疾病的发生密切相关。长时程增强（Long-term potentiation, LTP）是突触可塑性的一种分子模式，是目前公认的用来研究学习记忆的理想模型。对于LTP相关机制的研究成为目前神经生物学研究的热点。本文总结了近年来对LTP相关分子机制的最新研究进展，以期为临床治疗相关疾病提供新的思路。
It has been proved that synaptic plasticity is closely related to Alzheimer disease, epilepsy, chronic pain, drug addiction and so on. Long-term potentiation (LTP) is a molecular model of synaptic plasticity, which is an acknowledged ideal model to study learning and memory. In the last few decades great thrust has been put into studying LTP and correlated mechanism in the area of neurobiology. This article is a summary of studies for LTP related molecular mechanism to provide a novel approach to the treatment of clinical diseases.
王麟鹏、石广霞、李倩倩、刘存志
神经病学、精神病学基础医学分子生物学
突触可塑性长时程增强海马研究进展分子机制
synaptic plasticityLTPhippocampusmolecular mechanismresearch progress
王麟鹏,石广霞,李倩倩,刘存志.LTP的分子机制研究进展[EB/OL].(2012-05-09)[2025-08-24].http://www.paper.edu.cn/releasepaper/content/201205-134.点此复制
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