通过α-卤代酰腙与偶氮酯的[4+2]环加成反应合成1,2,3,4-四嗪类化合物

1,2,3,4-Tetrazine derivative is a kind of nitrogen-rich compounds, which exhibits higher energetic density and potential application on the field of energy materials. In this manuscript, though the [4+2] cycloaddition of alpha-halo-N-acylhydrazones to diazodicarboxylates, various 1,2,3,4-tetrazine derivatives could be afforded in good to excellent yields. Meanwhile, this reaction exhibits mild reaction conditions. The 1,2-diaza-1,3-dienes were generated in situ with the help of base, subsequently, in the absence of catalyst, the [4+2] cycloaddition proceeds well. Besides, this reaction could be performed on the gram scale and has good substrate scope.