成年牦牛感染扩展莫尼茨绦虫对小肠黏膜免疫相关细胞数量的影响

he histology, histochemistry and cell counting methods were used to evaluate the effects of Moniezia expansa on the number of mucosal immunity-associated cells in small intestine of adult yaks, 40 adult yaks were studied, 20 of them were infected with Moniezia expansa naturally, and the others were healthy. The number of intraepithelial lymphocyte(IEL), eosinophils, goblet cells, plasma cells and mast cells were counted, recorded, and compared with the normal group. Statistical analysis showed that the number of those mucosal immunity-associated cells were all increased in the infected group, compared with the normal group, and the difference was statistically significant（P<0.05）. The distribution tendency of those cells in small intestine was that: the number of intraepithelial lymphocyte(IEL), goblet cells and mast cells was gradually reduced from duodenum to ileum in two groups, whereas, the number of eosinophils and plasma cells was gradually increased from duodenum to ileum. The results indicated that Moniezia expansa has intense influence on the number of mucosal immunity-associated cells in small intestine of adult yaks, the hyperplasia of those cells can strengthen the anti-infections ability of adult yaks. It is showed that the anti-infection ability of the intestinal mucous membrane of adult yak is strong. Our results will facilitate our understanding of mucosal immunity-associated cells in small intestine of adult yaks and their role in immune response against Moniezia expansa.