EGFL7与肿瘤研究新进展

EGFL7 protein is a factor specially secreted by the endothelial cell. It is necessary for formation of vascular lumen, the formation process would be blocked and functions of vascular is incompleted if it is missing. it can be found in the early stage of embryo, but only found in few organs in adult, such as heart, lung and kidney. The level of EGFL7 protein is also high in the carcinoma and inflammatory tissues. The angiogenesis is very important for tumor’s growth and metastasis, EGFL7 expression blocked in tumor neovascularization can inhibite it’s growth and matastasis, it will give us a new way for tumor treatment.and matastasis it will give us a new way for tumor treatment.