针刺人迎穴对自发性高血压大鼠血管紧张素II的影响

Objective: To detect effects of acupuncturing Renying(ST9) on angiotensin II of spontaneously hypertensive rats.Methods: 30 male SHR rats and 10 WKY rats of 16-week-old (220-270 g) were selected. 30 SHR rats were randomized into 3 groups (model group, acupuncture group and captopril group). Rats in Renying group would be acupunctured on bilateral Renying； Rats in captopril group would be administrated with captopril; SHRs in model group and WKY rats would only be handled and restrained with same intense and strength. All intervention would be implemented from Monday to Friday for four weeks. Blood sample would be collected for measurement of ANGII level in plasma after four weeks' intervention. Results: the ANGII level in Renying group were significant lower than those of rats in model group (p<0.05), and has no significant difference with WKY group.Conclusion: Acupuncturing Renying (ST9) could significantly decrease the ANGII level in plasma, which indicates that the antihypertensive effect of Renying(ST9) might attribute to regulating the ANGII level