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基于房室模型的药时曲线研究

he Study of Drug Concentration-time Curve Based on Compartment Model

中文摘要英文摘要

药物疗效问题是药物动力学和药理学里面非常重要的一个研究课题,本文选用房室模型中的单室模型,对药物疗效问题进行了研究,并结合具体实例,首先用基本方法求出药时曲线的系数,给出了各种情况下药物在血液里面的浓度曲线,然后对结果进行了分析,引入了差值方法从而对初步求解结果进行修正,最终得到了药物在人体内循环的大体规律。

he problem of drug efficacy is a very important research topic in drugs and pharmacology pharmacokinetics. The paper studies the issues of drug efficacy base on the single-chamber model.And obtains drugs concentration curves in the blood and the general disciplines of drugs in the body cycle combined with concrete examples.

郑卫国、田其冲、李小翠

医药卫生理论医学研究方法药学

曲线拟合单室模型药时曲线插值法

urve fittingSingle-chamber modelrug concentration-time curveifference method

郑卫国,田其冲,李小翠.基于房室模型的药时曲线研究[EB/OL].(2009-06-09)[2025-08-02].http://www.paper.edu.cn/releasepaper/content/200906-258.点此复制

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