基于近红外光驱动的纳米马达用于复杂生物体液的葡萄糖检测
Near Infrared Light-Powered Nanomotor for Glucose Detection of Biological Fluids
葡萄糖作为一种重要的生物标志物,在人血液、尿液和脑脊液等体液中的含量映射了人体的健康情况,而葡萄糖检测在糖尿病的治疗中尤为重要。随着纳米技术的日益发展,目前已开发出多种基于电化学或光学的纳米传感器用于葡萄糖水平的检测,但是这种传感器在复杂的生物体液中对葡萄糖的检测仍十分困难,因此我们构建了一种基于荧光信号的纳米马达传感器,在近红外光的照射下纳米马达的自驱动能力可实现复杂的生物介质中葡萄糖水平的检测。实验结果表明在近红外光照下纳米马达传感器对葡萄糖的响应速度更快,灵敏度更高。这种纳米马达有望成为在复杂生物环境中检测标志物的有利工具。
s an important biomarker, glucose level in body fluids such as blood, urine and cerebrospinal fluid reflects human health, and the detection of glucose level is a key step in the treatment of diabetes. With the increasing development of nanotechnology, a variety of nanosensors based on electrochemistry or optics have been developed for the detection of glucose level. However, it\'s still very difficult for this sensor to detect glucose in complex biological fluid, we have constructed a nanomotor sensor based on fluorescence signal, which can detect the glucose level in complex biological media under the irradiation of near-infrared light. The experimental results show that the nanomotor sensor has faster response speed and higher sensitivity to glucose under near-infrared light. Nanomotor is expected to become an effective tool for detecting markers in complex biological environment.
吴禹、薛伟伟、魏为力
生物科学研究方法、生物科学研究技术生物化学生物物理学
葡萄糖、纳米马达、近红外光、荧光信号
glucosenanomotornear-infrared lightfluorescence signal
吴禹,薛伟伟,魏为力.基于近红外光驱动的纳米马达用于复杂生物体液的葡萄糖检测[EB/OL].(2022-04-01)[2025-08-23].http://www.paper.edu.cn/releasepaper/content/202204-24.点此复制
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