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原发性肝癌的流行病学及其危险因素研究进展

Research Progress in Epidemiology and Risk Factors of Primary Liver Cancer

中文摘要英文摘要

原发性肝癌是世界上最常见的恶性肿瘤之一,具有极高的发病率和死亡率。本文详述了目前我国原发性肝癌的流行病学情况、人群归因分值及其相关危险因素。本文通过检索PubMed、WebofScience、中国知网(CNKI)等数据库发现,乙型肝炎病毒和丙型肝炎病毒仍是原发性肝癌发病的主要危险因素。随着乙型肝炎病毒疫苗接种以及抗病毒治疗,我国原发性肝癌的发病率略有下降,但代谢性因素如糖尿病、肥胖和非酒精性脂肪性肝病等引起的原发性肝癌的发病率正逐步上升;吸烟、饮酒等也是重要的危险因素。本文综述了原发性肝癌的流行病学特点及危险因素,可为制订原发性肝癌防控措施提供切实有力的循证医学证据。

Primary liver cancer is one of the most common cancers in the world and with extremely high morbidity and mortality. This paper details the current epidemiology of primary liver cancerpopulation attributable fractions and associated risk factors in China. In this paperwe found that hepatitis B virus and hepatitis C virus are still the main risk factors for the development of primary liver cancer by searching the databases such as PubMedWeb of Scienceand CNKI. With hepatitis B virus vaccination and antiviral treatmentthe incidence of primary liver cancer in China has slightly decreasedbut the incidence of primary liver cancer caused by metabolic factors such as diabetesobesity and non-alcoholic fatty liver disease is gradually increasingsmoking and alcohol consumption are also important risk factors. This article summarizes the epidemiological characteristics and risk factors of primary liver cancerwhich can provide practical evidence-based medicine evidence for the development of preventive and control measures for primary liver cancer.

倪文婧、陈倩倩、芮法娟、李婕

10.12114/j.issn.1007-9572.2023.0479

肿瘤学预防医学基础医学

肝肿瘤原发性肝癌流行病学危险因素人群归因分值综述

Liver neoplasmsPrimary liver cancerEpidemiologyRisk factorsPopulation attribution fractionReview

倪文婧,陈倩倩,芮法娟,李婕.原发性肝癌的流行病学及其危险因素研究进展[EB/OL].(2023-09-08)[2025-08-02].https://chinaxiv.org/abs/202309.00089.点此复制

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