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水溶性L-半胱氨酸碳微球衍生物的合成及结构表征

he Synthesis and Structural Characterization of Water-soluble L-Cystine CMS Derivatives

中文摘要英文摘要

本文利用对人体肝脏具有特殊生物学效应的L-半胱氨酸制备了水溶性碳微球衍生物。采用化学气相沉积法(CVD),以乙炔为碳源,氩气为载气,二茂铁为催化剂制备了碳微球。利用硝酸对碳微球进行酸洗处理后,采用化学方法将L-半胱氨酸加成到碳微球的表面合成L-半胱氨酸碳微球衍生物,并通过扫描电子显微镜(SEM)、X射线衍射(XRD)、红外光谱(IR)等各种检测手段表征所制备的衍生物。结果表明,采用CVD法制备了表面光滑和粒径较均一的碳微球;酸洗处理和水溶性修饰没有破坏碳微球的结构,从而表明碳微球具有稳定的化学性能;修饰后产物表面具有—OH、—NH3等亲水性基团,使得疏水性的碳微球形成了水溶性良好的L-半胱氨酸碳微球衍生物。

In this paper, the water-soluble derivatives of carbon microspheres was prepared by L-cysteine which was very important to human liver. Carbon microspheres were synthesized by CVD method using acetylene as carbon source, argon as carrier gas and ferrocene as catalyst. Then the carbon microspheres were treated with nitrate and chemically modified with L-cysteine to prepare Water-soluble L-cystine CMS Derivatives (WLCMS). The samples were analyzed and characterized by XRD, FESEM and IR as followed. The results showed that the CVD method prepared carbon microspheres which have smooth surface and uniform particle size; pickling treatment and water-soluble carbon-modified microspheres did not damage the structure, thus demonstrating the stability of the carbon microspheres with chemical properties; hydrophilic groups added into the surface of carbon microspheres such as —OH, —NH3 made WLCMS be a good water-soluble derivatives.

张宏伟、张红鸽、王晓敏

生物化学化学生物科学研究方法、生物科学研究技术

碳微球衍生物L-半胱氨酸结构表征表面修饰

arbon microspheres derivativesL-cysteineStructural characterizationSurface modification

张宏伟,张红鸽,王晓敏.水溶性L-半胱氨酸碳微球衍生物的合成及结构表征[EB/OL].(2010-03-31)[2025-08-19].http://www.paper.edu.cn/releasepaper/content/201003-1127.点此复制

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