基于BB-SIR方法的结肠癌特征基因提取
Refinement procedure for eigen genes of colon carcinoma based on BB-SIR
结合复杂数据分析(Complex Data Analysis)理论和充分降维的思想,本文在有效提取结肠癌特征基因研究的基础上,建立结肠癌特征基因提取的BB-SIR模型。该模型方法简洁易懂且有较高的识别率。本文依据BB-SIR模型和所给数据找到了两个结肠癌亚型,并确定了该亚型的特征基因。实验结果表明,BB-SIR方法选出的特征基因能够识别出结肠癌亚型,并且识别正确率达到96%以上。
In this paper, new model of refining eigen genes of colon carcinoma, Bhattacharyya-Bootstrap-SIR, was established based on the study of sufficient refinement of eigen genes of colon carcinoma, combined theory of complex data analysis and sufficient dimension reduction. The model, called BB-SIR in brief, is easy to understand and has high rate of recognization. Two sub-colon carcinomas is founded by using the BB-SIR model and the sample data, futhermore we determined the eigen genes of two sub-colon carcinomas. The result showed that BB-SIR model can find the eigen genes of colon carcinma and can specify the two sub-colon carcinomas, the correct rate of recognization is at least as high as 96%.
唐胜男、邓丽君、李杰
肿瘤学生物科学研究方法、生物科学研究技术基础医学
特征基因结肠癌BB-SIR
Eigen genesolon carcinomaBB-SIR
唐胜男,邓丽君,李杰.基于BB-SIR方法的结肠癌特征基因提取[EB/OL].(2011-03-25)[2025-08-02].http://www.paper.edu.cn/releasepaper/content/201103-1008.点此复制
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