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Sleep quality does not mediate the association between chronodisruption and metabolic syndrome

Sleep quality does not mediate the association between chronodisruption and metabolic syndrome

来源:medRxiv_logomedRxiv
英文摘要

ABSTRACT AimsThe objective of the present work was to determine to what extent sleep quality may mediate the association between CD, metabolic syndrome (MS) and body composition (BC). MethodologyCross-sectional study which included 300 adult health workers, 150 of whom were night shift workers and thereby exposed to CD. Diagnosis of MS was made based on Adult Treatment Panel III criteria. Sleep quality was measured using the Pittsburgh Sleep Quality Index. Body mass index (BMI), fat mass percentage, and visceral fat percentage were measured as indicators of BC. Data were analyzed using logistic, linear regression and structural equation models. ResultsThe odds of health workers exposed to CD to suffer from MS was 22.13 (IC95 8.68 - 66.07) when the model was adjusted for age, gender, physical activity and energy consumption. CD was also significantly associated with an increase in fat mass and visceral fat percentages, but not to BMI. Surprisingly, there was not enough evidence supporting the hypothesis that sleep quality contributes to the association between CD and MS or BC. ConclusionsSleep quality does not mediate the negative effects of CD on health and BC.

Carpio-Arias Tannia Valeria、Arias Diana Carolina Mogrovejo、Nicolalde-Cifuentes Tomas Marcelo、Vinueza-Veloz Mar¨aa Fernanda、Tapia-Veloz Estephany Carolina、De Zeeuw Chris I.

Research group GIANH, Escuela Superior Polit¨|cnica de Chimborazo||Public Health Research Group, Universidad de AlicanteFaculty of Mathematics and Natural Sciences, University of PotsdamSchool of Medicine, Escuela Superior Polit¨|cnica de ChimborazoSchool of Medicine, Escuela Superior Polit¨|cnica de Chimborazo||Department of Neuroscience, Erasmus University Rotterdam||Research group PSICOMED, Escuela Superior Polit¨|cnica de ChimborazoDepartment of Pharmacy and Pharmaceutical Technology and Parasitology, University of ValenciaDepartment of Neuroscience, Erasmus University Rotterdam

10.1101/2020.10.30.20223164

医学研究方法医药卫生理论

shift workmetabolic syndromesleep qualitychronodisruption

Carpio-Arias Tannia Valeria,Arias Diana Carolina Mogrovejo,Nicolalde-Cifuentes Tomas Marcelo,Vinueza-Veloz Mar¨aa Fernanda,Tapia-Veloz Estephany Carolina,De Zeeuw Chris I..Sleep quality does not mediate the association between chronodisruption and metabolic syndrome[EB/OL].(2025-03-28)[2025-04-30].https://www.medrxiv.org/content/10.1101/2020.10.30.20223164.点此复制

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