173 例病理性乳头溢液临床病理特点及诊治分析

Objection:To investigate the clinical and pathological features and the follow-ups of 173 patients with pathological nipple discharge,and to provide the evidence of diagnosis and treatment.Methods:We reviewed the data of the patients who suffered pathological nipple discharge and as well underwent surgery in 2015.Statistical analysis was conducted by spss 22.0.T test and Mann-Whitney U test,X2 test and Fisher exact test were engaged in mean comparision,comparision of count data.Result: There were no statistically significant difference in ageunilateral/ bilateral single/multiple symptoms, duration of symptoms, positive findings of physical examination and Mammography between patients with bloody nipple discharge or not. Ultrasound revealed more positive findings in patients with bloody nipple discharge (P=0.016). Compared with unbloody discharge ,patients with bloody discharge showed higher rate of breast cancer(P=0.048).Among patients with bloody discharge, ages were significantly different between patients with and without breast cancer (P= 0.014) .Other factors showed no difference.Overall, no local or systemic recurrence or death was observed at a median follow-up of 17months. Conclusion: Bloody nipple discharge showed more risk of breast cancer, especially for the elder patients. Ultrasound revealed more lumps than physical examination and mammography. Since the examinations could not find the malignant lesions out of the symptoms of nipple discharge, surgery was always needed.