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硫酸酯化多糖抗病毒活性及其构效关系研究进展

Progress in Sulfated Polysacchrides Antiviral Activity and Strcture-activity

中文摘要英文摘要

天然的或经分子修饰后形成的硫酸酯化多糖是一种重要的具有生理活性的物质,例如具有抗病毒、抗肿瘤、抗炎、抗凝血、抗氧化、增强人体免疫力等多种功能。近年来硫酸酯化多糖的抗病毒活性一直备受关注,本文综述了硫酸酯化多糖的抗病毒活性及其构效关系的研究进展,为更好的寻找筛选新型糖类抗病毒药物提供了理论指导。

he sulfated polysaccharides, natural or formed by molecular modification,is an important material which possess biological activities.Such as antiviral activity 、antitumor、 anti -inflammtory 、anticlotting 、antioxidant 、enhance human immunity.In recent years, the antiviral activity of sulfated polysaccharides had been focused on. Structure-activity relationship and antiviral activity of sulfated polysaccharides were reviewed,and the study provided theoretical guidance for objective screening of sulfated polysaccharides.

刘瑞、楚慧丽、毛华、耿越

基础医学生物化学药学

硫酸酯化多糖抗病毒活性构效关系

sulfated polysaccharidesantiviral activitystructure-activity relationship

刘瑞,楚慧丽,毛华,耿越.硫酸酯化多糖抗病毒活性及其构效关系研究进展[EB/OL].(2010-07-27)[2025-08-18].http://www.paper.edu.cn/releasepaper/content/201007-492.点此复制

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