麻醉药对肾脏的损伤作用
Kidney Injury Caused by Anesthetics
麻醉药可能引起肾脏损伤。尤其是吸入麻醉药代谢过程中所产生的无机氟离子,可以导致机体尿量和溶质排泄的改变,甚至对肾脏组织造成直接的毒性作用。一些麻醉药也可通过影响循环系统、交感神经系统、内分泌系统等,对肾脏造成损伤。明确麻醉药对肾脏功能与结构影响的机制,对麻醉药的正确应用,减少副作用有重要意义。本文主要综述麻醉药对肾脏的损伤及其机制。
nesthetics might cause kidney injury. Especially the fluoride produced in the metabolic process of inhalation anesthetics can change urinary output and solute excretion, even cause direct nephrotoxicity. And some anesthetics also can cause kidney injury by affecting circulatory system, sympathetic nervous system and endocrine system. It is important to know the mechanisms of kidney injury for the correct use of anesthetics and avoiding the side effects. This review mainly focuses on kidney injury caused by anesthetics, and summarizes related mechanisms.
杨宝学、苏丽敏
基础医学临床医学药学
麻醉药肾脏氟
anestheticskidneyfluoride
杨宝学,苏丽敏.麻醉药对肾脏的损伤作用[EB/OL].(2013-12-26)[2025-08-16].http://www.paper.edu.cn/releasepaper/content/201312-879.点此复制
评论