氧化应激与阿尔茨海默病

lzheimer disease (AD) is a neurodegenerative disorder, characterized by a progressive loss in memory and cognitive function, sometimes accompanied by personal mental disorder. It has attracted the attention of many scientists nowadays, but the main mechanism is still unclear. Oxidative stress is one of the theories of AD etiology, which refers to the imbalance of oxidation and anti-oxidation, generating a large amount of intermediate. The accumulation of free radicals caused by oxidative stress is considered as an important factor in AD. This review deals with the close relationship between oxidative stress and AD, as well as the assessment of status of oxidative stress. Meanwhile, further studies of oxidative stress will provide approaches to cure AD.