MiR-126与眼科疾病的研究进展
Research Progress Mir-126 and Ophthalmic Diseases
目前已发现多种microRNA，其中miR-126在肿瘤细胞的增殖、胸腺淋巴细胞的发育、心血管疾病中发挥一定的作用。越来越多的研究表明有多种miRNA在视网膜神经上皮、晶状体、角膜和视网膜色素上皮中有特异性表达。大量实验发现miR-126与角膜新生血管的形成，糖尿病视网膜病变的发展，及免疫系统相关的眼科疾病均有一定的相关性。现就miR-126在眼科疾病的研究进展作一综述。
t present, many kinds of miRNA have been found, among which miR126 plays a certain role in the proliferation of tumor cells, the development of thymus lymphocytes and cardiovascular diseases. More and more studies show that there are many kinds of microRNA specially express in the retinal nerve epithelium, lens, cornea and retinal pigment epithelium. A large number of researches have found that the certain correlation of miR-126 with corneal neovascularization , the development of diabetic retinopathy, and immune system related eye diseases. This review about the research progress of miR-126 in ophthalmic diseases.
宋凡倩、孙莉尧、高宁宁、田甜、葛红岩、唐颖
眼科学
miR-126VEGF角膜新生血管角膜移植排斥糖尿病视网膜病变年龄相关性黄斑变性Vogt-小柳原田综合征眼部肿瘤
miR-126VEGForneal NeovascularizationCorneal Transplantation Rejectioniabetic Retinopathyge-related Macular DegenerationVogt-Koyanagi-HaradaEye tumour
宋凡倩,孙莉尧,高宁宁,田甜,葛红岩,唐颖.MiR-126与眼科疾病的研究进展[EB/OL].(2016-11-11)[2025-08-16].http://www.paper.edu.cn/releasepaper/content/201611-162.点此复制
评论