Neural networks implicated in autobiographical memory training
Neural networks implicated in autobiographical memory training
Abstract Training of autobiographical memory has been proposed as intervention to improve cognitive functions. The neural substrates for such improvements are poorly understood. Several brain networks have been previously linked to autobiographical recollections, including the default mode network (DMN) and the sensorimotor network. Here we tested the hypothesis that different neural networks support distinct aspects of memory improvement in response to training on a group of 59 subjects. We found that memory training increases DMN connectivity, and this associates with improved recollection of cue-specific memories. On the contrary, training decreased connectivity in the sensorimotor network, a decrease that correlated with improved ability for voluntary recall. Moreover, only decreased sensorimotor connectivity associated with training-induced decrease in the TNFα immunological factor, which has been previously linked to improved cognitive performance. We identified functional and biochemical factors that associate with distinct memory processes improved by autobiographical training. Pathways which connect autobiographical memory to both high level cognition and somatic physiology are discussed.
Sofonea Alexandra、Pu?ca?u Nicoleta、Papasteri Claudiu C.、Georgescu Dana、Tanase Dumitru、R?deanu Teofila、Toader Maria-Yaelle、Podin? Ioana R.、Berceanu Alexandru I.、Poalelungi Catalina、C?rneci Drago?、Dogaru Andreea L.、Onu Mihaela、Carcea Ioana
CINETic Center, University of Theatre and Film ?°I.L. Caragiale?± BucharestCINETic Center, University of Theatre and Film ?°I.L. Caragiale?± BucharestCINETic Center, University of Theatre and Film ?°I.L. Caragiale?± Bucharest||Department of Psychology, University of BucharestProvita Medical CenterCINETic Center, University of Theatre and Film ?°I.L. Caragiale?± BucharestDepartment of Psychology and Educational Sciences, Spiru Haret UniversityDepartment of Psychology and Educational Sciences, Spiru Haret UniversityCINETic Center, University of Theatre and Film ?°I.L. Caragiale?± Bucharest||Department of Psychology, University of BucharestCINETic Center, University of Theatre and Film ?°I.L. Caragiale?± BucharestCINETic Center, University of Theatre and Film ?°I.L. Caragiale?± BucharestCINETic Center, University of Theatre and Film ?°I.L. Caragiale?± Bucharest||Department of Psychology and Educational Sciences, Spiru Haret UniversityDepartment of Psychology and Educational Sciences, Spiru Haret UniversityCINETic Center, University of Theatre and Film ?°I.L. Caragiale?± Bucharest||Medical Imaging Department, Clinical Hospital ?°Prof. dr. Th. Burghele?±CINETic Center, University of Theatre and Film ?°I.L. Caragiale?± Bucharest||Department of Pharmacology, Physiology and Neuroscience, Rutgers Brain Health Institute, Rutgers, The State University of New Jersey
神经病学、精神病学基础医学生物科学研究方法、生物科学研究技术
autobiographical memorymemory trainingneural networks
Sofonea Alexandra,Pu?ca?u Nicoleta,Papasteri Claudiu C.,Georgescu Dana,Tanase Dumitru,R?deanu Teofila,Toader Maria-Yaelle,Podin? Ioana R.,Berceanu Alexandru I.,Poalelungi Catalina,C?rneci Drago?,Dogaru Andreea L.,Onu Mihaela,Carcea Ioana.Neural networks implicated in autobiographical memory training[EB/OL].(2025-03-28)[2025-05-28].https://www.biorxiv.org/content/10.1101/2021.10.05.463255.点此复制
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