牙髓再生治疗术研究新进展

Root canal treatment(RCT), as a conventional treatment method of pulpal inflammatory diseases, through infected tissue removal, root canal obturation, is used to maintain the teeth masticatory function. However, tooth fracture combined with host immune reactions occurs after RCT. With the rapid development of tissue engineering and cell biology, endodontic regeneration becomes the promising new strategy for treatments of pulpal diseases. Endodontic regeneration makes use of stem cells, biological growth factors and scaffolds to form a live tooth with vital pulpal tissue consisting of vascular system and nerves, together with the function of dentin formation. Therefore, this review focuses on the development of endodontic regeneration, current breakthrough and challenges in future researches.