微创与开腹膀胱造口手术对小型猪应激反应的影响

14 healthy miniature pigs were selected and randomly divided into two groups, Laparoscopic Cystostomy group and Open Cystostomy group. By detecting the change of the different time points after surgery of the miniature pig's Serum cortisol (COR), Interleukin - 6 (IL - 6) and C-reactive protein (CRP), Comparative the effects of traditional Open Cystostomy and laparoscopic Cystostomy on the body's stress response. The results show that LC and OC in the two groups at different time points respectively detected by COR, IL - 6 and CRP compared with before the trial, has the extremely significant difference (P < 0.01). In the immediate postoperative, the affect on stress index show that 4h OC group is significantly higher than the LC group, and postoperative 3d the LC group are restored to the level of before the experiment, while the OC group did not resume after 5d. Description LC and OC can lead to increase of serum COR, IL-6 and CRP levels. but OC compared with LC for COR, IL-6 and CRP affect the more significant that the Laparoscopic Cystostomy than Open Cystostomy affect the body's stress response is smaller.