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首页|P681 mutations within the polybasic motif of spike dictate fusogenicity and syncytia formation of SARS CoV-2 variants

P681 mutations within the polybasic motif of spike dictate fusogenicity and syncytia formation of SARS CoV-2 variants

Taube Ran Korovin Dina Mandelboim Michal Atari Nofar Rosental Benyamin lass Ido Cohen Ottolenghi Aner Rosenberg Elli Kuzmina Alona

P681 mutations within the polybasic motif of spike dictate fusogenicity and syncytia formation of SARS CoV-2 variants

Taube Ran 1Korovin Dina 2Mandelboim Michal 3Atari Nofar 4Rosental Benyamin 1lass Ido Cohen 1Ottolenghi Aner 2Rosenberg Elli 5Kuzmina Alona1

作者信息

  • 1. The Shraga Segal Department of Microbiology Immunology and Genetics Faculty of Health Sciences, Ben-Gurion University of the Negev
  • 2. The Shraga Segal Department of Microbiology Immunology and Genetics Faculty of Health Sciences, Ben-Gurion University of the Negev||Regenerative Medicine and Stem Cell Research Center, Ben Gurion University of the Negev
  • 3. Central Virology Laboratory, Public Health Services, Ministry of Health and Sheba Medical Center||Department of Epidemiology and Preventive Medicine, School of Public Health, Sackler Faculty of Medicine
  • 4. Central Virology Laboratory, Public Health Services, Ministry of Health and Sheba Medical Center
  • 5. Soroka Medical Center
  • 折叠

Key words

SARS CoV-2/Fusion and Syncytia/Pfizer-BTN162b2/neutralization antibodies/Furin-Cleavage Site/Poly basic domain

引用本文复制引用

Taube Ran,Korovin Dina,Mandelboim Michal,Atari Nofar,Rosental Benyamin,lass Ido Cohen,Ottolenghi Aner,Rosenberg Elli,Kuzmina Alona.P681 mutations within the polybasic motif of spike dictate fusogenicity and syncytia formation of SARS CoV-2 variants[EB/OL].(2025-03-28)[2025-12-13].https://www.biorxiv.org/content/10.1101/2022.04.26.489630.

学科分类

基础医学/分子生物学/微生物学

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首发时间 2025-03-28
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