脑出血后血红蛋白及降解产物毒性作用

Intracerebral hemorrhage (ICH) is a stroke subtype that characterized by a high morbidity and mortality The mechanism of brain injury following ICH are very complicated. The early stages of hematoma compression cause deformation and mechanical injury to local brain tissues.Secondary neuronal damage is caused by direct toxicity and inflammatory responses induced by the components and metabolic products of late-stage hematomas and aggravates neurologic deficits Red blood cells（RBC） is the main component of blood, Hemoglobin is produced after RBC degradation，together with its degradation products induces toxicity reaction，and lead to a series of brain damage.