穴位埋线对慢性心力衰竭大鼠心室重构的影响

Objective: Research the effect of Catgut Implantation at Acupoint on the ventricular remodeling in chronic congestive heart failure(CHF) rats. Methods: SD female rats were deviated randomly into 4 groups, 15 rascience of acupuncture and moxibustion；catgut implantation at acupoint；congestive heart failure(CHF)；ventricular remodeling；echocardiogram； cardiac sonographyts each group: sham-operation group(A), CHF model group(B), CHF model treated by catgut implantation at acupoint group(Catgut implantation group, C), CHF model treated by Captopril group(Captopril group, D). Suprarenal abdominal artery constriction was operated to prepare CHF rat models. After 7 week treating respectively, cardiac sonography were carried out, the left ventricular end-diastolic dimension(LVDd) and interventricular septum end-diastole thinkness(IVSTd) were measured，the end-diastole volume(EDV), ejection fraction(EF), left ventricular fraction shortening(FS)，and the left ventricular mass index(Im,LV) were calculated. Results:①Im,LV, LVDd, IVSTd and EDV in group B were higher than in group A (P<0.05 or P<0.01), while these in group C, D were respectively lower than in group B(P<0.05 or P<0.01). ②EF and FS in group B were all lower than in group A (P<0.01), EF in group C was higher than in group B (P<0.05 ), EF in group D was not higher than in group B(P>0.05), FS in group C and D had a tendency of being higher than group B (P>0.05). Conclusion: Catgut implantation at acupoint can meliorate the function of cardiac ejection and the structure of the heart in chronic congestive heart failure rat, and have the effect of against ventricular remodeling.