林下参助HaCaT细胞抗氧化损伤过程中的物理特性研究

he purpose of this study is to explore the protective effect of Panax ginseng extract on ethanol-induced oxidative stress damage in HaCaT.First, 6% ethanol was used to establish a cell oxidative damage model. After successful modeling, the cells were divided into 3 groups: group A was blank control, group B was model control, and group C was Panax ginseng extract. The cell viability was measured by MTT colorimetry, the morphological changes of cells were studied by SEM, and the Young\'s modulus, roughness, adhesion and height changes of the cells were studied by AFM. The HaCaT cell activity of different doses of ginseng extract group was higher than that of model control group. The integrity of the extracellular matrix of HaCaT cells in the different doses of group C was significantly higher than that of group B, and gradually approached group A. The height of cells in group C with different doses was lower than that of the model control group, and the Young\'s modulus, adhesion and cell membrane roughness were higher than group B. And the young\'s modulus, height, adhesion and membrane roughness of cells in group C were similar to group A. According to the results, Panax ginseng extract has a certain protective effect on the oxidative damage of HaCaT cells induced by ethanol.