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EB病毒和自身免疫病

Epstein- Barr Virus and Autoimmunity

中文摘要英文摘要

EB病毒(Epstein-Barr Virus, EBV)属疱疹病毒科,1964年由Epstein和Barr在研究非洲儿童恶性淋巴瘤时发现的一种感染人类B淋巴细胞的疱疹病毒,被国际癌症研究机构(International Agency for Research on Cancer, IARC)归为I类致癌物质,在全世界人群中感染率超过90%。自身免疫疾病(autoimmune diseases)是指机体对自身抗原发生免疫反应而导致自身组织损害所引起的疾病。本文综述了EB病毒与多种自身免疫疾病,如系统性红斑狼疮、多发性硬化症、类风湿性关节炎、自身免疫甲状腺病及自免性肝疾病之间的关系,并尝试用Pender的假说,解释这一现象。

EB virus is a human B-lymphocyte affinitive Herpesviridae, discovered in 1964 by Epstein and Barr during their research of African children malignant lymphoma, which is now defined as type I carcinogen by International Agency for Research on Cancer (IARC). EB infection rate among people in the world is over 90%. Autoimmune diseases are caused by the body\\\

金蕊、曾毅、马雪梅

基础医学肿瘤学神经病学、精神病学

EB病毒系统性红斑狼疮多发性硬化症类风湿性关节炎自身免疫甲状腺病及自免性肝疾病自身免疫疾病

Epstein- Barr VirusSystemic Lupus ErythematosusMultiple SclerosisRhumatic Arthritisutoimmune Thyroid Diseaseutoimmune liver diseaseutoimmune disease

金蕊,曾毅,马雪梅.EB病毒和自身免疫病[EB/OL].(2009-06-19)[2025-08-16].http://www.paper.edu.cn/releasepaper/content/200906-556.点此复制

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