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半枝莲活性成分抗动脉粥样硬化研究进展

dvances in studies on active ingredients of Scutellaria barbata against atherosclerosis

中文摘要英文摘要

半枝莲是一种常用中药,但其活性成分和抗动脉粥样硬化的机理尚不清晰。随着中药现代技术地应用,对其化学成分进行了深入分析,发现其主要生理活性物质是黄酮类化合物和多糖类化合物。药理研究表明,半枝莲活性成分主要通过调节脂质代谢反应和消除炎症反应达到抗动脉粥样硬化的作用。研究黄芩属植物半枝莲主要活性成分提取物及其抗动脉粥样硬化机制,为进一步对半枝莲进行新药研究和开发提供依据。

he Scutellaria barbata is a commonly used traditional Chinese medicine, its active ingredients and anti-atherosclerosis mechanism is still not clear. With the modern technology application in the traditional Chinese medicine research, its chemical composition is in-depth analysed, the main physiologically active substances are flavonoids and polysaccharides compounds. Pharmacological studies have shown that the anti-atherosclerotic role of the Scutellaria barbata active ingredient is mainly achieved through the regulation of lipid metabolism reaction and the elimination of the inflammatory response. The research on the mechanism of the Scutellaria barbata main active ingredient extract in anti-atherosclerosis is to provide the basis for further drug research and development.

郑新梅、卜平、祝娉婷、孙云

中医学基础医学药学

半枝莲化学成分动脉粥样硬化药理作用

Scutellariae barbataechemical ingredientatherosclerosispharmacological effects

郑新梅,卜平,祝娉婷,孙云.半枝莲活性成分抗动脉粥样硬化研究进展[EB/OL].(2013-02-15)[2025-08-02].http://www.paper.edu.cn/releasepaper/content/201302-270.点此复制

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