复方浙贝颗粒治疗难治性急性白血病中医证候疗效观察

o investigate the effect of the combination use of FTBCG with routine chemotherapeutics and seek why it can be effective from the view of the traditional Chinese medicine..METHODS: We adopted double-blind technique, many centre and random sampling for contrast. Separated 21 refractory acute leukemia patients into two teams, the therapy group(11cases,Fritillaria Thunbergii Bulb Complex Granules.po based on standard chemotherapeutics)and the control group(10cases,base on standard chemotherapeutics) .All cases were request to take their drug in 3 days before chemotherapy begins(10g t.i.d.) and take medicine for 14 days continuously. In this period,they don’t use any medicine which can reverses leukemia MDR..RESULTS: The score of the tranditional Chinese symptom show that in treatment group the effective cases are 63.6% ,the unavailing cases are36.6%. In the control group the effective cases are 10.0%, the unavailing cases are 90.0%. Comparing the total effective rate, there is statistical difference, P<0.05, the treatment group is better than the control group obviously.CONCLUSION: It was found that Fritillaria Thunbergii Bulb Complex Granules(FTBCG) of Refractory acute leukemia(RAL) could decrease the score of the tranditional Chinese symptom, and improve the patients’living standard.