慢性阻塞性肺疾病并发骨质疏松的常见原因分析
hronic obstructive pulmonary disease concurrent osteoporosis common reasons for analysis
慢性阻塞性肺疾病(chronic obstructive pulmonary disease,COPD)与骨质疏松(Ostocpoorsis,OP)均为常见性、多发性疾病。COPD具有较高的病死率,在全球范围内,己成为老年人死亡的第四位原因。骨质疏松被认为是世界上发病率、死亡率高及保健费用消耗大的疾病。?COPD患者容易继发骨质疏松的原因是多方面的, 吸烟、低氧血症与高碳酸血症、营养不良与低体重、废用性萎缩、糖皮质激素的应用、免疫因素和细胞因子的作用、内分泌功能紊乱、维生素D缺乏等等被认为是COPD继发OP的危险因素。总之,COPD患者急性加重的各种原因及各种病理改变互为因果,形成恶性循环,加快和加重了骨质疏松的病情及发展过程。
hronic obstructive pulmonary disease and osteoporosis are common multiple diseases. COPD has high fatality rate in the global scope, has become the fourth reason death among old people. Osteoporosis is considered one of the highest world morbidity, mortality diseases. The reason patients with COPD can easily secondary osteoporosis are considered as followed: smoking, hypoxia and hypercapnia, malnutrition and low weight, with atrophy of glucocorticoid applications, immune factors and cytokines function, endocrine dysfunction, and vitamin D deficiency, etc. Anyhow, COPD patients with acute exacerbation of all causes and various pathological changes reciprocal causation-the actual, form vicious circle, accelerate and aggravates osteoporosis condition and development process.
李红、汪为民
内科学
慢性阻塞性肺疾病骨质疏松原因
hronic obstructive pulmonary diseaseOsteoporosishe causes
李红,汪为民.慢性阻塞性肺疾病并发骨质疏松的常见原因分析[EB/OL].(2010-12-14)[2025-08-02].http://www.paper.edu.cn/releasepaper/content/201012-462.点此复制
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