Accurate and efficient protein sequence design through learning concise local environment of residues
Ye Sheng 1Zhang Haicang 2Fan Tingwen 3Qi Yangshuo 4Han Jian 3Fan Zheng 5Sun Shiwei 2Nie Shuyu 4Wang Kaiyue 1Zheng Wei-Mou 6Bu Dongbo 2Yu Chungong 7Huang Bin 8Yang Huaiyi9
作者信息
- 1. Beijing Advanced Innovation Center for Big Data-Based Precision Medicine, School of Engineering Medicine, Beihang University||Key Laboratory of Big Data-Based Precision Medicine (Beihang University), Ministry of Industry and Information Technology of the People?ˉs Republic of China
- 2. Key Lab of Intelligent Information Processing, SKLP, Institute of Computing Technology, Chinese Academy of Sciences||Zhongke Big Data Academy||University of Chinese Academy of Sciences
- 3. Key Lab of Microbial Physiological & Metabolic Engineering, State Key Lab of Mycology, Institute of Microbiology, Chinese Academy of Sciences
- 4. Key Lab of Microbial Physiological & Metabolic Engineering, State Key Lab of Mycology, Institute of Microbiology, Chinese Academy of Sciences||School of Life Sciences, Hebei University
- 5. Institutional Center for Shared Technologies and Facilities, Institute of Microbiology, Chinese Academy of Sciences
- 6. Institute of Theoretical Physics, Chinese Academy of Sciences||University of Chinese Academy of Sciences
- 7. Key Lab of Intelligent Information Processing, SKLP, Institute of Computing Technology, Chinese Academy of Sciences||Zhongke Big Data Academy
- 8. Key Lab of Intelligent Information Processing, SKLP, Institute of Computing Technology, Chinese Academy of Sciences||University of Chinese Academy of Sciences
- 9. Key Lab of Microbial Physiological & Metabolic Engineering, State Key Lab of Mycology, Institute of Microbiology, Chinese Academy of Sciences||University of Chinese Academy of Sciences
- 折叠
Key words
protein sequence design/local environment/transformer/deep learning引用本文复制引用
Ye Sheng,Zhang Haicang,Fan Tingwen,Qi Yangshuo,Han Jian,Fan Zheng,Sun Shiwei,Nie Shuyu,Wang Kaiyue,Zheng Wei-Mou,Bu Dongbo,Yu Chungong,Huang Bin,Yang Huaiyi.Accurate and efficient protein sequence design through learning concise local environment of residues[EB/OL].(2025-03-28)[2025-12-13].https://www.biorxiv.org/content/10.1101/2022.06.25.497605.学科分类
生物工程学/生物科学研究方法、生物科学研究技术/生物化学
评论