慢性阻塞性肺疾病患者的认知损害与脑源性神经营养因子表达水平之间关系的研究进展
Relationship between cognitive impairment and brain-derived neurotrophic factor levels with chronic obstructive pulmonary disease patients
认知功能的下降是慢性阻塞性肺疾病(COPD)患者常见的并发病，主要表现为学习、记忆等功能的缺失，这可能与年龄、吸烟、受教育程度以及COPD所致的低血氧低血流等因素损伤脑组织有关。本文主要从低血氧、低血流对神经系统损害，以及脑源性神经营养因子(BDNF)如何在这些不利因素中发挥保护神经细胞作用等方面作一综述。
ognitive impairment, which is a common comorbiditie in COPD patients, is characterized by the deletion of learning,memory and so on. Maybe these comorbidities are correlated with age, smoking, education, hypoxemia and/or hypoperfusion caused by COPD and so on. This article contains that how hypoxemia and hypoperfusion affect the central nervous system and how BDNF protect the nerves from these adverse factors.
林勇、汪群
内科学神经病学、精神病学基础医学
OPDBDNF低血氧低灌注认知功能
OPDBDNFhypoxemiahypoperfusionognition
林勇,汪群.慢性阻塞性肺疾病患者的认知损害与脑源性神经营养因子表达水平之间关系的研究进展[EB/OL].(2010-06-12)[2025-06-04].http://www.paper.edu.cn/releasepaper/content/201006-269.点此复制
评论