aveolin-1调控干细胞作用的研究进展
he role of caveolin-1 in stem cells function
aveolin-1是细胞膜结构胞膜窖的重要组成蛋白，参与了胆固醇的运输、细胞信号的传导、细胞增殖、肿瘤生成、细胞内吞等生物学过程。本文总结了caveolin-1在胚胎干细胞、造血干细胞、神经干细胞、间充质干细胞等细胞增殖和分化的调节作用及其相关的下游信号通路。研究caveolin-1在不同干细胞中的调节作用对于干细胞治疗和再生医学中会发挥重要作用。
aveolin-1 is a 22 kDa protein in the plasma membrane invaginations. Caveolin-1 is involved in the regulation of many cellular processes, including cholesterol regulation, cell signaling, cell growth, tumor and endocytosis etc. In this paper, we summarized the role of caveolin-1 in the regulation of embryonic stem cells, hemopoietic stem cells, neural stem cells and mesenchymal stem cells proliferation and differentiation.
白琳
基础医学细胞生物学分子生物学
caveolin-1干细胞增殖分化
aveolin-1stem cellproliferationdifferentiation
白琳.aveolin-1调控干细胞作用的研究进展[EB/OL].(2015-06-29)[2025-07-25].http://www.paper.edu.cn/releasepaper/content/201506-350.点此复制
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