1990-2019年中国蛋白质-能量营养不良发病趋势分析及预测
背景 蛋白质-能量营养不良(Protein-energy malnutrition,PEM)是常见的营养缺乏症之一,随着生活方式以及饮食习惯的改变,人们日益增加了对营养健康问题的关注度,而该疾病可对不同年龄人群的健康产生不同程度影响。近年来发病趋势,不同年龄的发病状况及相关预测有待分析研究。目的 通过对1990年至2019年中国PEM的发病和变化趋势进行分析,了解不同年龄的PEM发病状况,并预测到2029年的未来趋势,为PEM的预防提供依据。方法 根据2019年全球疾病负担(GBD 2019)研究的数据,利用 Joinpoint软件,对1990~2019年PEM各年龄段发病率以及年龄标准化发病率拟合对数线性模型,分析其变化趋势。用年度百分比变化(Annual percentage change,APC)和年度平均百分比变化(Average annual percentage change,AAPC)以及95%置信区间(Confidence interval,CI)来描述每个指标的趋势。利用ARIMA模型,预测了中国2020~2029年PEM的发病率趋势。结果 2019年中国全人群PEM标化发病率为1996.5/10万,男性高于女性,小于5岁人群PEM发病率最高(4402.5/10万),其次是80~84岁,5岁以后,无论男女其发病率均随年龄的不断增加而增高。中国PEM标化发病率结果显示:1990~1995年和2010~2014年中国PEM标化发病率呈现下降趋势。中国PEM年龄别发病率结果显示:1990~2019年小于5岁的人群以年平均变化2.1%的速度下降,其余各年龄段年均变化呈现整体平稳上升趋势。通过ARIMA模型预测结果显示,到2029年,中国的PEM发病率将达到7280.06/10万。结论 1990年以来,中国PEM发病率一直呈现平稳上升的趋势。并且到2029年,在中国大陆的发病率仍会继续上升。本研究将会为制定相关政策提供参考,为PEM的预防提供依据。
Background Protein-energy malnutrition (PEM) is one of the common nutritional deficiencies, and with changes in lifestyle and dietary habits, people are increasingly concerned about nutritional health issues, and the disease can affect the health of different age groups to varying degrees. Recent trends in morbidity, age-specific morbidity status and related predictions need to be analyzed and studied.Objective Protein-energy malnutrition (PEM) is one of the common nutritional deficiencies. By analyzing the incidence and changing trends of PEM in China from 1990 to 2019, we can understand the incidence of PEM at different ages and predict the future trends until 2029, and provide a basis. Methods Based on data from the Global Burden of Disease 2019 (GBD 2019) study, a log-linear model was fitted to the incidence rate of PEM by age and the age-standardized incidence rate from 1990 to 2019 using Joinpoint software to analyze the trends. Annual percentage change (APC) and average annual percentage change (AAPC) and 95% confidence intervals(95%CI) were used to describe the trends of each indicator. Using the ARIMA model, the trend of PEM incidence in China from 2020 to 2029 was predicted. Results The standardized incidence of PEM in the whole population in China in 2019 was 1996.5/100,000, with males higher than females, and the highest incidence of PEM in people younger than 5 years old (4402.5/100,000), followed by 80-84 years old, and after 5 years old, its incidence increased with increasing age in both sexes. The results of the standardized incidence rate of PEM in China showed that the standardized incidence rate of PEM in China showed a decreasing trend from 1990 to 1995 and from 2010 to 2014. The results of the age-specific incidence rate of PEM in China showed that the population younger than 5 years of age declined at an average annual change of 2.1% from 1990 to 2019, and the remaining age groups showed an overall stable upward trend in the average annual change. The prediction results by ARIMA model showed that the incidence rate of PEM in China will reach 7280.06/100,000 by 2029. Conclusion Since 1990, the incidence of PEM in China has been showing a steady increasing trend. And the incidence rate will continue to increase in mainland China by 2029. This study will provide a reference for the development of relevant policies and provide a basis for PEM prevention.
王红心, 樊文龙, 杨晓雨, 陈东宇, 黄巧, 潘素跃, 王朴, 胡敏, 何玉清
10.12114/j.issn.1007-9572.2022.0556
预防医学医药卫生理论医学研究方法
关键词:蛋白质-能量营养不良发病趋势Joinpoint回归模型RIMA模型
王红心, 樊文龙, 杨晓雨, 陈东宇, 黄巧, 潘素跃, 王朴, 胡敏, 何玉清.1990-2019年中国蛋白质-能量营养不良发病趋势分析及预测[EB/OL].(2022-08-01)[2025-08-18].https://chinaxiv.org/abs/202208.00019.点此复制
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