深部脑刺激下神经元电活动有限元仿真

eep brain stimulation is a novel and effective method to treat Parkinson, intractable epilepsy and other neurological disorders. But its mechanism is still not clear. A practical way to analyze the mechanism of deep brain stimulation is with the computer simulation analysis. Based on the stimulation of electric filed distribution in the brain with the finite element, this paper studies the impact of neuronic diameter and various electric stimulation modes on the neuron electric activity under different electrode-brain interface. This study provides a theoretical guidance for analyzing deep brain stimulation mechanism, electrode design and the simulation parameters selection.