The interdomain helix between the kinase and RNase domains of IRE1α transmits the conformational change that underlies ER stress-induced activation
Eletto Daniela 1Ricci Daniela 1Blumenthal Daniel 1Boyle Sarah 1Paton Adrienne W. 2Andrew Hu Chih-Chi 3Ying Mingjie 4Anthony Tang Chih-Hang 3Gidalevitz Tali 4Tutton Stephen 1Argon Yair 1Marrocco Ilaria 1Vargas Jade 1Fazelinia Hossein 1Paton James C.2
作者信息
- 1. Division of Cell Pathology, the Children?ˉs Hospital of Philadelphia and the University of Pennsylvania
- 2. Research Centre for Infectious Diseases, Department of Molecular and Biomedical Science, University of Adelaide
- 3. Wistar Institute
- 4. Department of Biology, Drexel University
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Key words
Kinase RNase interdomain helix/RNase activity/IRE1 oligomerization/differential autophosphorylation/conformational change引用本文复制引用
Eletto Daniela,Ricci Daniela,Blumenthal Daniel,Boyle Sarah,Paton Adrienne W.,Andrew Hu Chih-Chi,Ying Mingjie,Anthony Tang Chih-Hang,Gidalevitz Tali,Tutton Stephen,Argon Yair,Marrocco Ilaria,Vargas Jade,Fazelinia Hossein,Paton James C..The interdomain helix between the kinase and RNase domains of IRE1α transmits the conformational change that underlies ER stress-induced activation[EB/OL].(2025-03-28)[2025-12-13].https://www.biorxiv.org/content/10.1101/2020.01.14.902395.学科分类
基础医学/生物化学/分子生物学
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