膜联蛋白A的功能及研究意义

nnexin was first found in the late 1970s. It was a new class of membrane binding protein, accounting for around two percent of total cellular proteins. Annexin was generally existed in many kinds of organisms, such as plants, animals, and fungi. Moreover, annexin is a multiple protein families associated with membrane lipids and cytoskeleton. Its conservative structural domain was calcium-dependent, and participating of the various life activities, such as vesicle transport, signal transduction, calcium channel formation; also associated with the regulation of inflammation, the molecular growth mechanism of cancer cell and various pathological reactions. Based on the much more previous reports, this review was summarized the functions of annexin especially Annexin A associated with disease.