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Imputing phylogenetic trees using tropical polytopes over the space of phylogenetic trees

Imputing phylogenetic trees using tropical polytopes over the space of phylogenetic trees

来源:Arxiv_logoArxiv
英文摘要

When we apply comparative phylogenetic analyses to genome data, it is a well-known problem and challenge that some of given species (or taxa) often have missing genes. In such a case, we have to impute a missing part of a gene tree from a sample of gene trees. In this short paper we propose a novel method to infer a missing part of a phylogenetic tree using an analogue of a classical linear regression in the setting of tropical geometry. In our approach, we consider a tropical polytope, a convex hull with respect to the tropical metric closest to the data points. We show a condition that we can guarantee that an estimated tree from our method has at most four Robinson-Foulds (RF) distance from the ground truth and computational experiments with simulated data show our method works well.

Ruriko Yoshida

生物科学研究方法、生物科学研究技术数学

Ruriko Yoshida.Imputing phylogenetic trees using tropical polytopes over the space of phylogenetic trees[EB/OL].(2023-06-30)[2025-04-27].https://arxiv.org/abs/2306.17566.点此复制

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