多组分反应研究现状

Multicomponent Coupling Reactions ("one-pot" synthesis), that is to say, put three or more reactants in a reactor and give it some conditions to react. As its simple operation , easy-getting stuff, short reaction time and without seperating the intermediate, has been caused schoolar's attentions currently. As far, MCRs has been used in many fields, especially playde an important role in the pharmaceuticals synthesis. Recently, many methods have been reported. In this paper, the Multicomponent Coupling Reactions' development history, many other advantages and application in heterocycle compounds have been summarized. Particularly sum up the liquid and solid applications in the fields.