微生物分解代谢尼古丁调控机制研究进展

With the rise in global tobacco production and consumption, nicotine toxicity may be a leading cause of lung cancer, death and environmental pollution. A number of researchers focus on effectively controlling nicotine content in cigarettes and tobacco wastes. Several bacterial species, particularly those in the genera Arthrobacter and Pseudomonas, can use nicotine as their sole carbon and nitrogen source. Although a number of studies on biochemical and molecular nicotine degradation have been provided, the regulatory mechanism has not been well documented. This article briefly describes the progress in the regulation, mainly related to two operons in Arthrobacter, in order to provide a guide role on nicotine highly degradation.