305例胰腺癌中医证型分布规律及影响因素分析

Objective :To identify the distribution patterns of TCM symptoms and TCM syndromes in patients with pancreatic cancer,assess the correlation between TCM syndromes and various factors such as sex, age,the course of disease,presence of lymph node or distant metastasis and previous treatment,and provide the basis for clinical diagnosis and treatment of pancreatic cancer.Methods:Retrospectively analyzing the medical records of 305 patients with pancreatic cancer,basic information and TCM symptoms were be collected.The classification and diagnosis of 305 patient\'s TCM syndromes were made based on diagnostic criteria of TCM syndromes.Aescriptive statistics were applied to describe the distribution patterns of TCM symptoms and TCM syndromes,and analytical statistics were performed to assess the correlation between TCM syndromes and various factors such as sex,age,the course of disease,presence of lymph node or distant metastasis and previous treatment.Results:The results of study showed that,patients with pancreatic cancer experienced abdominal pain with bloating as the first symptom,and The primary clinical symptom were anorexia, fatigue and abdominal pain.The distribution of TCM syndromes ranged from high to low：damp retention due to spleen deficiency syndrome,dampness-heat amassment pattern syndrome,yin deficiency of liver and kidney syndrome,stagnation of qi and blood stasis syndrome,deficiency of both qi and blood syndrome,heat-toxin amassment and binding of static blood syndrome.The difference between the groups,grouped according to sex,age,the course of disease,presence of lymph node or distant metastasis and with or without surgery and chemotherapy,was statistically significant.Conclusions:The primary TCM syndromes were damp retention due to spleen deficiency syndrome,dampness-heat amassment pattern syndrome.Sex,age,the course of disease,presence of lymph node or distant metastasis and with or without surgery were factors affecting TCM syndromes of patients