胰岛素分泌细胞的研究进展

Cellular replacement offers the potential of a cure for diabetes mellitus. Shortage of suitable donors limits widespread application of this approach. Research has been focused on potential sources of insulin-secreting cells including differentiation of pancreas-derived stem cells, transdifferentiation of non pancreas-derived stem cells and somatic cells，islet β cell lines or non-islet β insulin-secreting cell lines and hybrid islet β cell lines with the development of molecular biology. In this review, we summarized the kinds of insulin-secreting cells in existence briefly.