LuftiBus in the school (LUIS): a population-based study on respiratory health in schoolchildren
LuftiBus in the school (LUIS): a population-based study on respiratory health in schoolchildren
Summary Respiratory disease is common in children and strongly associated with lifestyle and environmental exposures. Thus, it is important to study the epidemiology locally. LuftiBus in the school (LUIS) was set up to assess the respiratory health of schoolchildren in the canton of Zurich, Switzerland. LUIS is a cross-sectional population-based study that was carried out 2013 to 2016. Children aged 6-17 years living in the canton of Zurich were eligible to participate. All schools in the canton were approached and the school head decided whether the school would participate and with which classes. Consenting parents answered a standardized questionnaire at home and assenting children completed a shorter questionnaire by interview at school. Trained technicians measured children’s lung function including spirometry, double tracer gas single-breath washout (DTG-SBW) and fractional exhaled nitric oxide (FeNO). Address histories of participants were geocoded to be linked with area-based socioeconomic measures and environmental exposures like spatiotemporal air pollution estimates for specific time periods and locations. A subgroup was seen again 12 months later using the same procedures to collect longitudinal data. The study included 3870 children at baseline and 655 at the one-year follow-up. Median age was 12.7 years; 281 (8%) had wheezed in the past year. At baseline we collected 3457 (89%) parental and 3546 (92%) children’s questionnaires, and 3393 (88%) FeNO, 3446 (89%) spirometry, and 1795 (46%) DTG-SBW measurements. LUIS is a rich resource of health-related data, with information on lung function, environmental exposures and respiratory health on Swiss schoolchildren. Take home messageLuftiBus in the school (LUIS) is a population-based study with detailed lung function data and rich information on respiratory health in Swiss schoolchildren.
Pedersen Eva S. L.、Goutaki Myrofora、de Hoogh Kees、Singer Florian、Latzin Philipp、Mozun Rebeca、Kuehni Claudia E.、Usemann Jakob、Kurz Johanna M.、Moeller Alexander
Institute of Social and Preventive Medicine, University of BernInstitute of Social and Preventive Medicine, University of Bern||Paediatric Respiratory Medicine, Children?ˉs University Hospital of Bern, University of BernSwiss Tropical and Public Health Institute||University of BaselPaediatric Respiratory Medicine, Children?ˉs University Hospital of Bern, University of Bern||PEDNET, paediatric clinical trial unit, Children?ˉs University Hospital of Bern, University of BernPaediatric Respiratory Medicine, Children?ˉs University Hospital of Bern, University of BernInstitute of Social and Preventive Medicine, University of Bern||Graduate School for Cellular and Biomedical Sciences, University of BernInstitute of Social and Preventive Medicine, University of Bern||Paediatric Respiratory Medicine, Children?ˉs University Hospital of Bern, University of BernDivision of Respiratory Medicine, University Children?ˉs Hospital Zurich and Children?ˉs Research Center, University of Zurich||University Children?ˉs Hospital Basel (UKBB)Paediatric Respiratory Medicine, Children?ˉs University Hospital of Bern, University of BernDivision of Respiratory Medicine, University Children?ˉs Hospital Zurich and Children?ˉs Research Center, University of Zurich
医学研究方法预防医学环境科学理论
childrenrespiratory symptomslung function testsair pollution
Pedersen Eva S. L.,Goutaki Myrofora,de Hoogh Kees,Singer Florian,Latzin Philipp,Mozun Rebeca,Kuehni Claudia E.,Usemann Jakob,Kurz Johanna M.,Moeller Alexander.LuftiBus in the school (LUIS): a population-based study on respiratory health in schoolchildren[EB/OL].(2025-03-28)[2025-05-01].https://www.medrxiv.org/content/10.1101/2020.10.14.20212076.点此复制
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