吩噻/噁/硒嗪类化合物的3,7位芳基化反应

Phenothiazines have attracted widespread attention because of their unique skeleton structure, a molecule with potential biological and pharmacological activities, and have been widely used in biomedicine and optoelectronic materials. In this paper, a series of N-methyl-3,7-diaryl phenothiazine/oxa/selenazine compounds were obtained by using the Suzuki-Miyaura reaction to arylation at position 3 and 7 on the phenothiazine ring, thereby expanding the molecular library of phenothiazine compounds. In addition, the emission wavelength of these compounds is red-shifted using structural modification, which lays a foundation for the development of near-infrared fluorescent probes and biological imaging.