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Effectiveness of “Reducing Disability in Alzheimer’s Disease” among dyads with moderate dementia

Effectiveness of “Reducing Disability in Alzheimer’s Disease” among dyads with moderate dementia

来源:medRxiv_logomedRxiv
英文摘要

Abstract Interventions such as Reducing Disability in Alzheimer’s Disease (RDAD) improve the health of care receiver-caregiver dyads but plans to implement it locally in regional community agencies yielded three changes: 1) reduced reliance on licensed clinicians, 2) centralized exercise interventionists and 3) more flexible delivery. We aimed to assess the effectiveness of the Kansas City RDAD implementation (RDAD-KC) among a non-probabilistic sample of dyads with moderate dementia, which addressed these changes. We hypothesized that dyads’ health would improve from baseline to the end-of-treatment. Outcomes improved (p<0.01) from pre to post-intervention: Behavioral symptom severity (range 0-36) decreased from 11.3 to 8.6, physical activity increased from 125.0 to 190.0 minutes/week, caregiver unmet needs (range 0-34) decreased from 10.6 to 5.6, caregiver behavioral symptom distress (0-60) decreased from 15.5 to 10.4 and caregiver strain (0-26) decreased from 11.1 to 9.7. This adapted implementation of RDAD leads to clinically meaningful improvements and might inform scaling-up.

Neira Antonio Mir¨¢s、Vidoni Eric D、Perales-Puchalt Jaime、Barton Kelli、Niedens C. Michelle、Gilman Laura、Sprague Susan C.、Van Dyke Rik、Ptomey Lauren T、Seymour Pam、Teri Linda、Yeager Amy、George Amanda

KC Care Health CenterUniversity of Kansas Alzheimer?ˉs Disease CenterUniversity of Kansas Alzheimer?ˉs Disease CenterHealth and Aging Department, University of Missouri-Kansas City Institute for Human DevelopmentUniversity of Kansas Alzheimer?ˉs Disease CenterJewish Family ServicesOCCK Inc.Wyandotte/Leavenworth Area Agency on AgingDepartment of Internal Medicine, University of Kansas Medical CenterShepherd?ˉs Center of KC CentralUniversity of Washington School of NursingUniversity of Kansas Alzheimer?ˉs Disease CenterEmpowering Individuals Through Advocacy and Support (EITAS)

10.1101/2020.04.07.20056705

神经病学、精神病学医学研究方法

dementiacaregivingdyadseffectivenessimplementation

Neira Antonio Mir¨¢s,Vidoni Eric D,Perales-Puchalt Jaime,Barton Kelli,Niedens C. Michelle,Gilman Laura,Sprague Susan C.,Van Dyke Rik,Ptomey Lauren T,Seymour Pam,Teri Linda,Yeager Amy,George Amanda.Effectiveness of “Reducing Disability in Alzheimer’s Disease” among dyads with moderate dementia[EB/OL].(2025-03-28)[2025-05-13].https://www.medrxiv.org/content/10.1101/2020.04.07.20056705.点此复制

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