A minimum reporting standard for multiple sequence alignments
A minimum reporting standard for multiple sequence alignments
ABSTRACT Multiple sequence alignments (MSAs) play a pivotal role in studies of molecular sequence data, but nobody has developed a minimum reporting standard (MRS) to quantify the completeness of MSAs in terms of completely-specified nucleotides or amino acids. We present an MRS that relies on four simple completeness metrics. The metrics are implemented in AliStat, a program developed to support the MRS. A survey of published MSAs illustrates the benefits and unprecedented transparency offered by the MRS.
Yeates David K、Misof Bernhard、Meusemann Karen、Wong Thomas KF、Jermiin Lars S、Kalyaanamoorthy Subha
Australian National Insect Collection, CSIRO National Research Collections AustraliaZoologisches Forschungsmuseum Alexander KoenigAustralian National Insect Collection, CSIRO National Research Collections Australia||Zoologisches Forschungsmuseum Alexander Koenig||Evolutionsbiologie & ?kologie, Institut f¨1r Biologie I, Albert-Ludwigs-Universit?t FreiburgLand & Water, CSIRO||Research School of Biology, Australian National UniversityLand & Water, CSIRO||Research School of Biology, Australian National University||School of Biology and Environmental Science, University College Dublin||Earth Institute, University College DublinLand & Water, CSIRO||Department of Chemistry, University of Waterloo
分子生物学生物科学研究方法、生物科学研究技术
Multiple sequence alignmentscompletenessminimum reporting standard
Yeates David K,Misof Bernhard,Meusemann Karen,Wong Thomas KF,Jermiin Lars S,Kalyaanamoorthy Subha.A minimum reporting standard for multiple sequence alignments[EB/OL].(2025-03-28)[2025-05-01].https://www.biorxiv.org/content/10.1101/2020.01.15.907733.点此复制
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