中国年轻女性HPV疫苗接种意愿影响因素的探究及评估

HPV vaccination can not only effectively prevent the development of cervical cancer and its precancerous lesions, but also prevent other parts of the disease caused by HPV infection. However, the vaccination situation in China is not optimistic, and many young people are hesitant to get the HPV vaccine. Based on the planning theory model, this study aims to explore the influencing factors of HPV vaccination intention, compile a questionnaire with good reliability and validity to evaluate the importance of influencing factors of HPV vaccination intention, and explore the importance degree of influencing factors of different vaccination intention. In experiment 1, this study explored the influencing factors of individual HPV vaccination intention through semi-structured interview method, and obtained 25 influencing factors such as vaccine safety, vaccine effectiveness, vaccination convenience, professionalism, conformity and data. In experiment 2, through exploratory factor analysis, confirmatory factor analysis and reliability and validity test, a 17-question, 4-dimensional questionnaire was constructed to evaluate the importance of factors influencing HPV vaccination intention. Among them, confirmatory factor analysis supported the 4-factor model (/df<3, RMR=0.059, RMSEA=0.054, GFI=0.928, TLI=0.914, IFI=0.929), showing good model fit. The Cronbachs coefficient of the questionnaire was 0.853, and the retest reliability at a 4-week interval was 0.804. It shows that our questionnaire has good reliability and validity. In addition, there are significant differences in the evaluation of the importance of different influencing factors, and there are also significant differences in the evaluation of the importance of factors among individuals with or without a family history of cancer and different levels of education. This study will provide valuable insights into vaccination promotion strategies and provide scientific basis and reference for developing targeted approaches.