两种方法建立犬髂动脉狭窄模型的对比分析

Objective:The canine model with external iliac artery stenosis suitable for stent placement study were developed by balloon dilation and vascular suture separately, and the strongpoint and disadvantage of two methods are analyzed.Method: Ten canines were randomly divided into 2 groups. The weight is 15-20Kg.Treat bilateral external iliac arteries by balloon dilation and vascular suture separately. Stenosis rate was monitored by angiography after 3 months. The succeed rate of developing the model was compared, and the strongpoint and disadvantage of two methods are analyzed.Results: Ten external iliac arteries were treated with balloon dilation, the other ten were with vascular suture. The angiography after 3 months showed that balloon dilation developed 3 stenotic arteries, the stenosis rate was less than 30%; Vascular suture developed 8 stenotic arteries, the rate was more than 50%.Conclusion: The stenosis rate of balloon dilation was too low to suitable for developing canine iliac artery stenosis model. Vascular suture developed this model stably, but complicated manipulation and many complications were major disadvantages of this method.