聚酰胺-胺型树状分子功能化的钛酸盐纳米管修饰电极在增强鲁米诺电致化学发光中的应用

novel luminol electrochemiluminescent (ECL) sensor platform was constructed by poly(amidoamine) dendrimer (PAAD) functionalized titanate nanotubes (TNTs). Herein, the excellent synergetic effect between PAAD that with the quite open spherical 3 D structures possessing a high density of active groups was propitious to mass transportation and TNTs which possess excellent electronic conductivity promoted the electron transfer at the electrode surface contributed to obviously enhanced availability of electroactive surface capable and electronic conductivity of modified electrode. The effect factors such as the concentration of TNTs, the pH value of buffer solution and electrochemical parameters on ECL intensity of luminol at PAAD/TNTs modified GCE were also studied to obtain a sensitive ECL sensor which presented wide linear response range of luminol and would be further sensitized by hydrogen peroxide (H2O2). Furthermore, base on the quenching effect of superoxide dismutase (SOD) on H2O2-sensitized luminol ECL by the reason of the scavenging effect of SOD on superoxide anion, a sensitive SOD ECL biosensor was then developed and could be useful to reveal the amount of radicals generated which would result to diseases like atherosclerosis, rheumatoid arthritis and some tumours.