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胰腺癌基础研究进展

dvances in basic research of pancreatic cancer

中文摘要英文摘要

胰腺癌是最致命的胃肠道恶性肿瘤之一,近年来美国胰腺癌男女发病率每年上升约1%,而在我国,胰腺癌发病率位列第10位,死亡率位列第5位,5年相对生存率仅为 7.2%。在过去的二十年中,胰腺癌的死亡率和发病率一直在增加,我们迫切需要了解胰腺癌基础研究的进展。本文参考2020年胰腺癌相关基础研究报道,从基因组学、代谢组学、肿瘤微环境、预后因子及新靶标四个方面总结了胰腺癌基础研究进展并进行了综述。

Pancreatic cancer is one of the most deadly gastrointestinal cancer. In recent years, the incidence of pancreatic cancer in men and women in the United States has increased by about 1% every year.In China,pancreatic cancer ranks 10th for incidence and 5th for mortality, and the 5-year relative survival rate is only 7.2%.The mortality and incidence of pancreatic cancer have been increasing in the past two decades, and we urgently need to understand the progress of basic research on pancreatic cancer.Here we reviewed the latest high quality studies published in 2020,and summarized the progress in genomics, metabolomics, tumor microenvironment, prognostic factors and novel targets to provide theoretical support for conquering this lethal disease.

张静娴、李蕊白、吕丽媛、田劭丹

基础医学肿瘤学

肿瘤学胰腺癌基础研究进展

OncologyPancreatic cancerBasic researchProgress

张静娴,李蕊白,吕丽媛,田劭丹.胰腺癌基础研究进展[EB/OL].(2021-03-11)[2025-08-05].http://www.paper.edu.cn/releasepaper/content/202103-115.点此复制

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