磁场处理对壳聚糖金属配合物抑制大肠杆菌的影响
Effect of Magnetic Field on the Antibacterial Activities of
目的：壳聚糖（CS）是有丰富自然资源的甲壳素的脱乙酰基产物,壳聚糖及其衍生物具有优良的生物活性。本文报道了壳聚糖与铅、铜、铬等过渡金属离子所形成的壳聚糖金属配合物（CS-Cu、CS-Pb、CS-Cr）对大肠杆菌的抑制作用以及外加磁场处理对其抑菌作用的影响。方法：通过采用琼脂扩散纸片法测定各壳聚糖金属配合物对大肠杆菌的最低抑菌浓度，评价壳聚糖金属配合物的抑菌能力。结论：实验结果表明，各种壳聚糖金属配合物对大肠杆菌的抑制作用存在程度上的差异，以CS-Cr的抑菌效果最显著；外加磁场处理，能加强壳聚糖金属配合物对大肠杆菌的抑制作用，在场强为400kA/m的磁场作用下，各种壳聚糖金属衍生物对大肠杆菌的最低抑菌浓度分别为CS-Cu：12.5 mg/ml，CS-Pb：6.25 mg/ml，CS-Cr：3.125mg/ml。研究显示壳聚糖金属配合物在食品加工中有开发应用价值。
Objective: Chitosan is the product of deacetylation from chitin which has a enrich resource in nature. There are many excellent bioactivities and outstanding performances with chitosan and its derivates. The inhibitions of chitosan and the coordination complexes of chitosan with transition metal ions （CS-Cu、CS-Pb、CS-Cr）on Escherichia coli were reported. And the effects of extrinsic magnetic fields on the inhibitions were studied. Method: The minimum inhibition concentrations of chitosan metal complexes were determined using the agar diffusion paper method to estimate the antibacterial activities of these complexes on E. coli. Conclusions: It could be seen from the results that there were some differences of inhibition on E. coli for different complexes in varying degrees. In which, the CS-Cr was the best. The inhibitions on Escherichia coli could be enhanced by the magnetic treatment of 400kA/m. The minimum inhibitory concentrations of the chitosan metal complexes on E.coli were respectively as CS-Cu：12.5 mg/ml，CS-Pb：6.25 mg/ml，CS-Cr：3.125mg/ml. It showed a bright applied foreground for the chitosan metal complexes in food processing.
杨晋青、段丽红、肖凯军、郑必胜、郭祀远、王兆梅
生物科学现状、生物科学发展生物科学研究方法、生物科学研究技术微生物学
磁场壳聚糖金属配合物大肠杆菌抗菌抑菌活性
magnetic fieldchitosanmetal complexesEscherichia coliantibacterial and inhibition activities
杨晋青,段丽红,肖凯军,郑必胜,郭祀远,王兆梅.磁场处理对壳聚糖金属配合物抑制大肠杆菌的影响[EB/OL].(2009-01-19)[2025-07-22].http://www.paper.edu.cn/releasepaper/content/200901-885.点此复制
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