茶叶提取液对溶菌酶蛋白纤维化的影响

Protein fibrillation is relevant to numerous human diseases including the well-known diseases like Alzheimer's disease, Parkinson's disease, and type II diabetes. Searching for active organics for the inhibition of protein fibrillation is highly beneficial for the prevention and treatment of protein fibrillation relevant diseases. Using Thioflavin T fluorescence assay and atomic force microscopy, the inhibitory effects of the extract solutions from five different types of tea on the fibrillation of lysozyme were investigated. It was found that all of the five types of tea extract solutions showed inhibitory effects on protein fibrillation by lysozyme.